College of Science and Mathematics
34 achievements

34 achievements

Youn, Hwan
Benabbas, A., Karunakaran, V., Champion, P., Youn, H., & Poulos, T.  (2012). Effect of DNA binding on geminate CO recombination kinetics in CO-sensing transcription factor CooA.  Journal of Biological Chemistry. 287(26), 21729-21740.
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Karunakaran, V., Benabbas, A., Champion, P., & Youn, H.  (2011). Vibrational coherence spectroscopy of the heme domain in the co-sensing transcriptional activator CooA.  Journal of the American Chemical Society. 133(46), 18816-18827.
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Serate, J., Roberts, G., Berg, O., & Youn, H.  (2011). Ligand responses of Vfr, the virulence factor regulator from Pseudomonas aeruginosa.  Journal of Bacteriology. 193(18), 4859-4868.
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Youn, H., Serate, J., & Berg, O.  (2011). Contribution of Vfr’s unique ligand response to its physiological function. Presented at 111th American Society for Microbiology (ASM) General Meeting, New Orleans, Louisiana.
Youn, H., Hicks, M., & Serate, J.  (2010). Directed evolution of Escherichia coli cAMP receptor protein at the cAMP-binding pocket.  110th American Society for Microbiology (ASM). San Diego, California.
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Lee, A., Clark, R., Ponter, S., Burstyn, J., & Youn, H.  (2009). Guanidine hydrochloride-induced unfolding of the three heme coordination states of the CO-sensing transcription factor, CooA.  Biochemistry. 48(28), 6585-6597.
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Kerby, R., Youn, H., & Roberts, G.  (2008). RcoM: A new single-component transcriptional regulator of CO metabolism in bacteria.  Journal of Bacteriology. 190(9), 3336-3343.
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Marvin, K., Burstyn, J., Kerby, R., Youn, H., & Roberts, G.  (2008). The transcription regulator RcoM-2 from Burkholderia xenovorans is a cysteine-ligated hemoprotein that undergoes a redox-mediated ligand switch.  Biochemistry. 47(34), 9016-9028.
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Youn, H., Roberts, G., & Koh, J.  (2008). Two-state allosteric modeling suggests protein equilibrium as an integral component for cyclic AMP (cAMP) specificity in the cAMP receptor protein of Escherichia coli.  Journal of Bacteriology. 190(13), 4532-4540.
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Clark, R., Youn, H., Lee, A., Roberts, G., & Burstyn, J.  (2007). DNA binding by an imidazole-sensing CooA variant is dependent on the heme redox state.  Journal of Biological Inorganic Chemistry. 12(2), 139-146.
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Ibrahim, M., Kuchinskas, M., Youn, H., Kerby, R., Roberts, G., Poulos, T., & Spiro, T.  (2007). Mechanism of the CO-sensing heme protein CooA: New insights from the truncated heme domain and UVRR spectroscopy.  Journal of Inorganic Biochemistry. 101(11-12), 1776-1785.
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Youn, H., Kerby, R., Koh, J., & Roberts, G.  (2007). A C-helix Residue, Arg-123, Has Important Roles in Both the Active and Inactive Forms of the cAMP Receptor Protein.  Journal of Biological Chemistry. 282(6), 3632-3639.
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Ibrahim, M., Kerby, R., Puranik, M., Wasbotten, I., Youn, H., Roberts, G., & Spiro, T.  (2006). Heme displacement mechanism of CooA activation: Mutational and Raman spectroscopic evidence.  The Journal of biological chemistry. 281(39), 29165-73.
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Youn, H., Conrad, M., Chung, S., & Roberts, G.  (2006). Roles of the heme and heme ligands in the activation of CooA, the CO-sensing transcriptional activator.  Biochemical and Biophysical Research Communications. 348(2), 345-350.
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Youn, H., Kerby, R., Conrad, M., & Roberts, G.  (2006). Study of highly constitutively active mutants suggests how cAMP activates cAMP receptor protein.  The Journal of biological chemistry. 281(2), 1119-27.
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Roberts, G., Kerby, R., Youn, H., & Conrad, M.  (2005). CooA, a paradigm for gas sensing regulatory proteins.  Journal of Inorganic Biochemistry. 99(1), 280-92.
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Youn, H., Thorsteinsson, M., Conrad, M., Kerby, R., & Roberts, G.  (2005). Dual roles of an E-helix residue, Glu167, in the transcriptional activator function of CooA.  Journal of Bacteriology. 187(8), 2573-81.
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Clark, R., Youn, H., Parks, R., Cherney, M., Roberts, G., & Burstyn, J.  (2004). Investigation of the role of the N-terminal proline, the distal heme ligand in the CO sensor CooA.  Biochemistry. 43(44), 14149-60.
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Puranik, M., Nielsen, S., Youn, H., Hvitved, A., Bourassa, J., Case, M., ... Spiro, T.  (2004). Dynamics of carbon monoxide binding to CooA.  The Journal of Biological Chemistry. 279(20), 21096-108.
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Roberts, G., Youn, H., & Kerby, R.  (2004). CO-Sensing Mechanisms.  Microbiology and Molecular Biology Reviews. 68(3), 453-473.
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Youn, H., Kerby, R., Conrad, M., & Roberts, G.  (2004). Functionally critical elements of CooA-related CO sensors.  Journal of Bacteriology. 186(5), 1320-9.
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Youn, H., Kerby, R., & Roberts, G.  (2004). Changing the ligand specificity of CooA, a highly specific heme-based CO sensor.  The Journal of Biological Chemistry. 279(44), 45744-52.
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Coyle, C., Puranik, M., Youn, H., Nielsen, S., Williams, R., Kerby, R., ... Spiro, T.  (2003). Activation mechanism of the CO sensor CooA. Mutational and resonance Raman spectroscopic studies.  The Journal of Biological Chemistry. 278(37), 35384-93.
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Kerby, R., Youn, H., Thorsteinsson, M., & Roberts, G.  (2003). Repositioning about the dimer interface of the transcription regulator CooA: a major signal transduction pathway between the effector and DNA-binding domains.  Journal of Molecular Biology. 325(4), 809-23.
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Youn, H., Kerby, R., & Roberts, G.  (2003). The role of the hydrophobic distal heme pocket of CooA in ligand sensing and response.  The Journal of Biological Chemistry. 278(4), 2333-40.
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Youn, H., Kerby, R., Thorsteinsson, M., Clark, R., Burstyn, J., & Roberts, G.  (2002). Analysis of the L116K variant of CooA, the heme-containing CO sensor, suggests the presence of an unusual heme ligand resulting in novel activity.  The Journal of Biological Chemistry. 277(37), 33616-23.
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Thorsteinsson, M., Kerby, R., Youn, H., Conrad, M., Serate, J., Staples, C., & Roberts, G.  (2001). Redox-mediated transcriptional activation in a CooA variant.  The Journal of Biological Chemistry. 276(29), 26807-13.
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Youn, H., Kerby, R., Thorsteinsson, M., Conrad, M., Staples, C., Serate, J., ... Roberts, G.  (2001). The heme pocket afforded by Gly117 is crucial for proper heme ligation and activity of CooA.  The Journal of Biological Chemistry. 276(45), 41603-10.
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Thorsteinsson, M., Kerby, R., Conrad, M., Youn, H., Staples, C., Lanzilotta, W., ... Roberts, G.  (2000). Characterization of variants altered at the N-terminal proline, a novel heme-axial ligand in CooA, the CO-sensing transcriptional activator.  The Journal of Biological Chemistry. 275(50), 39332-8.
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Youn, H., & Kang, S.  (2000). Enhanced sensitivity of Streptomyces seoulensis to menadione by superfluous lipoamide dehydrogenase.  FEBS Letters. 472(1), 57-61.
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Cho, S., Na, J., Youn, H., Hwang, C., Lee, C., & Kang, S.  (1999). Sepiapterin reductase producing L-threo-dihydrobiopterin from Chlorobium tepidum.  The Biochemical Journal. 497-503.
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Cho, S., Na, J., Youn, H., Hwang, C., Lee, C., & Kang, S.  (1998). Tepidopterin, 1-O-(L-threo-biopterin-2'-yl)-b-N-acetylglucosamine from Chlorobium tepidum.  General Subjects. 1379(1), 53.
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Youn, H., Kwak, J., Youn, H., Hah, Y., & Kang, S.  (1998). Lipoamide dehydrogenase from streptomyces seoulensis: biochemical and genetic properties.  Biochimica et Biophysica Acta. 1388(2), 405-18.
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Youn, H., Youn, H., Lee, J., Yim, Y., Lee, J., Hah, Y., & Kang, S.  (1996). Unique Isozymes of Superoxide Dismutase in Streptomyces griseus.  Archives of Biochemistry and Biophysics. 334(2), 341.
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