College of Science and Mathematics
34 achievements
Benabbas, A., Karunakaran, V., Champion, P., Youn, H., & Poulos, T.
(2012).
Effect of DNA binding on geminate CO recombination kinetics in CO-sensing transcription factor CooA.
Journal of Biological Chemistry. 287(26),
21729-21740.
|
| Karunakaran, V., Benabbas, A., Champion, P., & Youn, H.
(2011).
Vibrational coherence spectroscopy of the heme domain in the co-sensing transcriptional activator CooA.
Journal of the American Chemical Society. 133(46),
18816-18827.
|
| Serate, J., Roberts, G., Berg, O., & Youn, H.
(2011).
Ligand responses of Vfr, the virulence factor regulator from Pseudomonas aeruginosa.
Journal of Bacteriology. 193(18),
4859-4868.
|
| Youn, H., Serate, J., & Berg, O.
(2011).
Contribution of Vfr’s unique ligand response to its physiological function.
Presented at
111th American Society for Microbiology (ASM) General Meeting, New Orleans, Louisiana. |
| Youn, H., Hicks, M., & Serate, J.
(2010).
Directed evolution of Escherichia coli cAMP receptor protein at the cAMP-binding pocket.
110th American Society for Microbiology (ASM).
San Diego, California.
|
| Lee, A., Clark, R., Ponter, S., Burstyn, J., & Youn, H.
(2009).
Guanidine hydrochloride-induced unfolding of the three heme coordination states of the CO-sensing transcription factor, CooA.
Biochemistry. 48(28),
6585-6597.
|
| Kerby, R., Youn, H., & Roberts, G.
(2008).
RcoM: A new single-component transcriptional regulator of CO metabolism in bacteria.
Journal of Bacteriology. 190(9),
3336-3343.
|
| Marvin, K., Burstyn, J., Kerby, R., Youn, H., & Roberts, G.
(2008).
The transcription regulator RcoM-2 from Burkholderia xenovorans is a cysteine-ligated hemoprotein that undergoes a redox-mediated ligand switch.
Biochemistry. 47(34),
9016-9028.
|
| Youn, H., Roberts, G., & Koh, J.
(2008).
Two-state allosteric modeling suggests protein equilibrium as an integral component for cyclic AMP (cAMP) specificity in the cAMP receptor protein of Escherichia coli.
Journal of Bacteriology. 190(13),
4532-4540.
|
| Clark, R., Youn, H., Lee, A., Roberts, G., & Burstyn, J.
(2007).
DNA binding by an imidazole-sensing CooA variant is dependent on the heme redox state.
Journal of Biological Inorganic Chemistry. 12(2),
139-146.
|
| Ibrahim, M., Kuchinskas, M., Youn, H., Kerby, R., Roberts, G., Poulos, T., & Spiro, T.
(2007).
Mechanism of the CO-sensing heme protein CooA: New insights from the truncated heme domain and UVRR spectroscopy.
Journal of Inorganic Biochemistry. 101(11-12),
1776-1785.
|
| Youn, H., Kerby, R., Koh, J., & Roberts, G.
(2007).
A C-helix Residue, Arg-123, Has Important Roles in Both the Active and Inactive Forms of the cAMP Receptor Protein.
Journal of Biological Chemistry. 282(6),
3632-3639.
|
| Ibrahim, M., Kerby, R., Puranik, M., Wasbotten, I., Youn, H., Roberts, G., & Spiro, T.
(2006).
Heme displacement mechanism of CooA activation: Mutational and Raman spectroscopic evidence.
The Journal of biological chemistry. 281(39),
29165-73.
|
| Youn, H., Conrad, M., Chung, S., & Roberts, G.
(2006).
Roles of the heme and heme ligands in the activation of CooA, the CO-sensing transcriptional activator.
Biochemical and Biophysical Research Communications. 348(2),
345-350.
|
| Youn, H., Kerby, R., Conrad, M., & Roberts, G.
(2006).
Study of highly constitutively active mutants suggests how cAMP activates cAMP receptor protein.
The Journal of biological chemistry. 281(2),
1119-27.
|
| Roberts, G., Kerby, R., Youn, H., & Conrad, M.
(2005).
CooA, a paradigm for gas sensing regulatory proteins.
Journal of Inorganic Biochemistry. 99(1),
280-92.
|
| Youn, H., Thorsteinsson, M., Conrad, M., Kerby, R., & Roberts, G.
(2005).
Dual roles of an E-helix residue, Glu167, in the transcriptional activator function of CooA.
Journal of Bacteriology. 187(8),
2573-81.
|
| Clark, R., Youn, H., Parks, R., Cherney, M., Roberts, G., & Burstyn, J.
(2004).
Investigation of the role of the N-terminal proline, the distal heme ligand in the CO sensor CooA.
Biochemistry. 43(44),
14149-60.
|
| Puranik, M.,
Nielsen, S.,
Youn, H.,
Hvitved, A.,
Bourassa, J.,
Case, M.,
... Spiro, T.
(2004).
Dynamics of carbon monoxide binding to CooA.
The Journal of Biological Chemistry. 279(20),
21096-108.
|
| Roberts, G., Youn, H., & Kerby, R.
(2004).
CO-Sensing Mechanisms.
Microbiology and Molecular Biology Reviews. 68(3),
453-473.
|
| Youn, H., Kerby, R., Conrad, M., & Roberts, G.
(2004).
Functionally critical elements of CooA-related CO sensors.
Journal of Bacteriology. 186(5),
1320-9.
|
| Youn, H., Kerby, R., & Roberts, G.
(2004).
Changing the ligand specificity of CooA, a highly specific heme-based CO sensor.
The Journal of Biological Chemistry. 279(44),
45744-52.
|
| Coyle, C.,
Puranik, M.,
Youn, H.,
Nielsen, S.,
Williams, R.,
Kerby, R.,
... Spiro, T.
(2003).
Activation mechanism of the CO sensor CooA. Mutational and resonance Raman spectroscopic studies.
The Journal of Biological Chemistry. 278(37),
35384-93.
|
| Kerby, R., Youn, H., Thorsteinsson, M., & Roberts, G.
(2003).
Repositioning about the dimer interface of the transcription regulator CooA: a major signal transduction pathway between the effector and DNA-binding domains.
Journal of Molecular Biology. 325(4),
809-23.
|
| Youn, H., Kerby, R., & Roberts, G.
(2003).
The role of the hydrophobic distal heme pocket of CooA in ligand sensing and response.
The Journal of Biological Chemistry. 278(4),
2333-40.
|
| Youn, H., Kerby, R., Thorsteinsson, M., Clark, R., Burstyn, J., & Roberts, G.
(2002).
Analysis of the L116K variant of CooA, the heme-containing CO sensor, suggests the presence of an unusual heme ligand resulting in novel activity.
The Journal of Biological Chemistry. 277(37),
33616-23.
|
| Thorsteinsson, M., Kerby, R., Youn, H., Conrad, M., Serate, J., Staples, C., & Roberts, G.
(2001).
Redox-mediated transcriptional activation in a CooA variant.
The Journal of Biological Chemistry. 276(29),
26807-13.
|
| Youn, H.,
Kerby, R.,
Thorsteinsson, M.,
Conrad, M.,
Staples, C.,
Serate, J.,
... Roberts, G.
(2001).
The heme pocket afforded by Gly117 is crucial for proper heme ligation and activity of CooA.
The Journal of Biological Chemistry. 276(45),
41603-10.
|
| Thorsteinsson, M.,
Kerby, R.,
Conrad, M.,
Youn, H.,
Staples, C.,
Lanzilotta, W.,
... Roberts, G.
(2000).
Characterization of variants altered at the N-terminal proline, a novel heme-axial ligand in CooA, the CO-sensing transcriptional activator.
The Journal of Biological Chemistry. 275(50),
39332-8.
|
| Youn, H., & Kang, S.
(2000).
Enhanced sensitivity of Streptomyces seoulensis to menadione by superfluous lipoamide dehydrogenase.
FEBS Letters. 472(1),
57-61.
|
| Cho, S., Na, J., Youn, H., Hwang, C., Lee, C., & Kang, S.
(1999).
Sepiapterin reductase producing L-threo-dihydrobiopterin from Chlorobium tepidum.
The Biochemical Journal. 497-503.
|
| Cho, S., Na, J., Youn, H., Hwang, C., Lee, C., & Kang, S.
(1998).
Tepidopterin, 1-O-(L-threo-biopterin-2'-yl)-b-N-acetylglucosamine from Chlorobium tepidum.
General Subjects. 1379(1),
53.
|
| Youn, H., Kwak, J., Youn, H., Hah, Y., & Kang, S.
(1998).
Lipoamide dehydrogenase from streptomyces seoulensis: biochemical and genetic properties.
Biochimica et Biophysica Acta. 1388(2),
405-18.
|
| Youn, H., Youn, H., Lee, J., Yim, Y., Lee, J., Hah, Y., & Kang, S.
(1996).
Unique Isozymes of Superoxide Dismutase in Streptomyces griseus.
Archives of Biochemistry and Biophysics. 334(2),
341.
|
